Description

2-(3,5-Dimethylbenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. Its unique molecular structure, featuring both a benzoyl and a protected aldehyde (dioxolane) group on a thiophene core, makes it a valuable building block for creating complex heterocyclic compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or with specific receptor-binding profiles.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, or insecticides, where the thiophene moiety contributes to biological activity.
• Material Science Research: Serves as a monomer or functional unit in the development of advanced organic electronic materials, such as semiconductors for OLEDs or organic photovoltaics (OPVs).
• Ligand and Catalyst Development: The structure can be utilized to create sophisticated ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific molecular targets.

Basic Information

Product Name	2-(3,5-Dimethylbenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene
CAS No.	898779-31-2
Molecular Formula	C16H16O3S
Molecular Weight	288.36 g/mol
Synonyms	5-(1,3-Dioxolan-2-yl)-2-(3,5-dimethylbenzoyl)thiophene; 2-(3,5-Dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 898779-31-2; 2-(3,5-Dimethylbenzoyl)thiophene-5-carboxaldehyde ethylene acetal; Thiophene, 2-(3,5-dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 2-(3,5-Dimethylbenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light). For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5% Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.