Description

2-(3,4-Dimethylbenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is a specialized organic compound featuring a thiophene core functionalized with a dimethylbenzoyl group and a protected aldehyde moiety, making it a valuable advanced intermediate in synthetic organic chemistry. Its precise molecular architecture is critical for constructing complex heterocyclic systems, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity building block is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, structurally-defined intermediates for sophisticated synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory activity.
• Agrochemical Research: Serves as a precursor for developing new herbicides, fungicides, or insecticides with unique modes of action, leveraging its heterocyclic structure.
• Material Science: Used in the research and development of organic electronic materials, such as organic semiconductors or light-emitting materials, due to its conjugated thiophene system.
• Chemical Synthesis: Acts as a versatile building block for constructing complex molecules in academic and industrial research laboratories for method development and library synthesis.
• Ligand & Catalyst Development: Potential utility in the design of novel ligands for metal catalysis or as a core structure for organocatalysts.

Basic Information

Product Name	2-(3,4-Dimethylbenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene
CAS No.	898779-28-7
Molecular Formula	C₁₈H₁₈O₃S
Molecular Weight	314.40 g/mol
Synonyms	5-(1,3-Dioxolan-2-yl)-2-(3,4-dimethylbenzoyl)thiophene; 2-(3,4-Dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 898779-28-7; 2-(3,4-Dimethylbenzoyl)thiophene-5-carboxaldehyde ethylene acetal; Thiophene, 2-(3,4-dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)-; 5-(1,3-Dioxolan-2-yl)-2-(3,4-dimethylphenyl)methanoylthiophene
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dimethylbenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.