Description

2-(3,5-Dimethoxybenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining thiophene and benzoyl moieties. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in research and development targeting novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes exploring new heterocyclic chemistry and bio-active molecule synthesis.
• Fine Chemical Production: Used in the manufacture of specialty chemicals and complex organic molecules for high-value applications.

Basic Information

Product Name	2-(3,5-Dimethoxybenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene
CAS No.	898779-13-0
Molecular Formula	C₁₈H₁₈O₅S
Molecular Weight	346.40 g/mol
Synonyms	5-(1,3-Dioxolan-2-yl)-2-(3,5-dimethoxybenzoyl)thiophene; 2-(3,5-Dimethoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; Thiophene, 2-(3,5-dimethoxybenzoyl)-5-(1,3-dioxolan-2-yl)-; CAS 898779-13-0
EINECS	Contact for details

Quality Control

Our 2-(3,5-Dimethoxybenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects with material suitable for research use and can supply material manufactured under cGMP guidelines for advanced clinical trials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; therefore, containers should be opaque or stored in darkness. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.