Description

2-(2,6-Difluorobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluorobenzoyl and dioxolane-substituted thiophene structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel, small-molecule drug candidates, especially in oncology and central nervous system (CNS) research.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides and fungicides with enhanced activity.
• Material Science: Used in the research and development of organic electronic materials and specialty polymers.
• Chemical Synthesis: An important reagent for constructing complex heterocyclic frameworks in medicinal and process chemistry.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and discovery chemistry.

Basic Information

Product Name	2-(2,6-Difluorobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene
CAS No.	898778-80-8
Molecular Formula	C₁₄H₁₀F₂O₃S
Molecular Weight	308.29 g/mol
Synonyms	2-(2,6-Difluorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(2,6-difluorobenzoyl)thiophene; Thiophene, 2-(2,6-difluorobenzoyl)-5-(1,3-dioxolan-2-yl)-; 898778-80-8; 2,6-Difluoro-5-(1,3-dioxolan-2-yl)thiophene-2-carbonylbenzene
EINECS	Contact for details

Quality Control

Every batch of 2-(2,6-Difluorobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is manufactured and tested under a strict quality management system. We ensure compliance with ICH guidelines and relevant industry standards for pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.