Description

2-(2,5-Difluorobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiophene and difluorobenzoyl structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel, fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms and heterocyclic core contribute to enhanced biological activity and stability.
• Material Science Precursor: Serves as a specialized monomer or precursor in the research of organic electronic materials, such as semiconductors and conductive polymers.
• Chemical Synthesis: Employed in organic chemistry laboratories for complex coupling reactions and as a scaffold for creating diverse heterocyclic libraries for high-throughput screening.

Basic Information

Product Name	2-(2,5-Difluorobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene
CAS No.	898778-78-4
Molecular Formula	C14H10F2O3S
Molecular Weight	296.29 g/mol
Synonyms	5-(1,3-Dioxolan-2-yl)-2-(2,5-difluorobenzoyl)thiophene; 2-(2,5-Difluorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; Thiophene, 2-(2,5-difluorobenzoyl)-5-(1,3-dioxolan-2-yl)-; 898778-78-4; 2,5-Difluoro-β-oxo-5-(1,3-dioxolan-2-yl)-2-thiophenepropiophenone
EINECS	Contact for details

Quality Control

Our production of 2-(2,5-Difluorobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.