Description

5-(1,3-Dioxolan-2-Yl)-2-(4-Isopropylbenzoyl)Thiophene is a high-value, specialized organic intermediate featuring a thiophene core functionalized with a protected carbonyl group and an isopropylbenzoyl moiety. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where precise molecular architecture is paramount. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries seeking to develop novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides or fungicides, leveraging the thiophene scaffold for bioactivity.
• Organic Electronic Materials: Acts as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) or organic photovoltaics (OPVs).
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis, facilitating challenging cross-coupling reactions.
• Chemical Research (R&D): A versatile scaffold for medicinal chemistry and material science research, enabling the exploration of structure-activity relationships (SAR).
• Fine Chemical Production: Integrated into multi-step synthetic routes for the production of complex, high-value specialty chemicals.

Basic Information

Product Name	5-(1,3-Dioxolan-2-Yl)-2-(4-Isopropylbenzoyl)Thiophene
CAS No.	898778-37-5
Molecular Formula	C₁₇H₁₈O₃S
Molecular Weight	302.39 g/mol
Synonyms	2-(4-Isopropylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(4-propan-2-ylbenzoyl)thiophene; 898778-37-5; Thiophene, 5-(1,3-dioxolan-2-yl)-2-[(4-isopropylphenyl)carbonyl]-; 2-(4-Isopropylbenzoyl)thiophene-5-carboxaldehyde ethylene acetal
EINECS	Contact for details

Quality Control

Our 5-(1,3-Dioxolan-2-Yl)-2-(4-Isopropylbenzoyl)Thiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.