Description

5-(1,3-Dioxolan-2-Yl)-2-(3-Nitrobenzoyl)Thiophene is a specialized heterocyclic organic compound featuring a thiophene core functionalized with both a protected aldehyde (dioxolane) and a nitrobenzoyl group. This unique structure makes it a valuable and versatile chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in the development of complex molecules requiring specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the thiophene and nitroaromatic motifs contribute to biological activity.
• Material Science Precursor: Serves as a monomer or functional unit in the research of organic semiconductors, conductive polymers, or non-linear optical (NLO) materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, such as Suzuki or Stille couplings, to construct complex biaryl systems for various research applications.
• Chemical Biology Probe Development: Utilized as a scaffold for creating fluorescent tags or molecular probes to study biological processes.

Basic Information

Product Name	5-(1,3-Dioxolan-2-Yl)-2-(3-Nitrobenzoyl)Thiophene
CAS No.	898778-31-9
Molecular Formula	C14H11NO5S
Molecular Weight	305.31 g/mol
Synonyms	2-(3-Nitrobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(3-nitrobenzoyl)thiophene; 3-Nitrobenzoylthiophene dioxolane derivative; Thiophene, 5-(1,3-dioxolan-2-yl)-2-(3-nitrobenzoyl)-; [898778-31-9]
EINECS	Contact for details

Quality Control

Every batch of 5-(1,3-Dioxolan-2-Yl)-2-(3-Nitrobenzoyl)Thiophene is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure high purity and batch-to-batch consistency for research and development purposes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere such as nitrogen or argon for long-term storage to maintain stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.