Description

5-(1,3-Dioxolan-2-Yl)-2-(4-Phenoxybenzoyl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a key building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for innovative synthesis pathways.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its thiophene and benzophenone motifs.
• Material Science: Potential building block for organic electronic materials, such as organic semiconductors or light-emitting diodes (OLEDs), due to its conjugated system.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and cross-coupling chemistry.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for target molecules in pilot plants.

Basic Information

Product Name	5-(1,3-Dioxolan-2-Yl)-2-(4-Phenoxybenzoyl)Thiophene
CAS No.	898778-28-4
Molecular Formula	C20H16O3S
Molecular Weight	336.40 g/mol
Synonyms	2-(4-Phenoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(4-phenoxybenzoyl)thiophene; 898778-28-4; 4-Phenoxy-α-(5-(1,3-dioxolan-2-yl)-2-thienyl)benzyl alcohol ketone derivative
EINECS	Contact for details

Quality Control

Our 5-(1,3-Dioxolan-2-Yl)-2-(4-Phenoxybenzoyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO standards ensures a reliable supply of this high-value intermediate for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.