Description

5-(1,3-Dioxolan-2-Yl)-2-(4-Iodobenzoyl)Thiophene is a high-value, multi-functional organic building block featuring a thiophene core substituted with both an iodobenzoyl and a protected aldehyde (dioxolane) group. This compound matters for its versatility in advanced organic synthesis, particularly in cross-coupling reactions where the iodine atom serves as an excellent leaving group. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those containing heterocyclic scaffolds for therapeutic applications.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging its reactive sites for structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials like OLEDs or semiconductors.
• Cross-Coupling Reactions: The iodine substituent makes it an ideal substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Synthesis: The protected aldehyde group allows for selective deprotection and further functionalization, enabling precise molecular construction.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis or as a core structure in catalyst design.

Basic Information

Product Name	5-(1,3-Dioxolan-2-Yl)-2-(4-Iodobenzoyl)Thiophene
CAS No.	898778-16-0
Molecular Formula	C₁₄H₁₁IO₃S
Molecular Weight	386.21 g/mol
Synonyms	2-(4-Iodobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(4-iodobenzoyl)thiophene; 898778-16-0; 4-Iodobenzoyl Thiophene Derivative; Thiophene, 5-(1,3-dioxolan-2-yl)-2-(4-iodobenzoyl)-; (4-Iodophenyl)[5-(1,3-dioxolan-2-yl)-2-thienyl]methanone
EINECS	Contact for details

Quality Control

Our 5-(1,3-Dioxolan-2-Yl)-2-(4-Iodobenzoyl)Thiophene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.