Description

5-(1,3-Dioxolan-2-Yl)-2-(2-Iodobenzoyl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities in medicinal chemistry research. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its thiophene and iodobenzoyl motifs.
• Material Science Precursor: Serves as a monomer or precursor for organic electronic materials, such as conductive polymers and organic semiconductors.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) due to the presence of the iodine substituent, facilitating complex molecular construction.
• Academic & Industrial R&D: Essential for method development and exploratory synthesis in university and corporate research laboratories.
• Ligand and Catalyst Development: Used to create novel ligands for transition metal catalysis in asymmetric synthesis.

Basic Information

Product Name	5-(1,3-Dioxolan-2-Yl)-2-(2-Iodobenzoyl)Thiophene
CAS No.	898778-10-4
Molecular Formula	C₁₄H₁₁IO₃S
Molecular Weight	386.21 g/mol
Synonyms	2-(2-Iodobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(2-iodobenzoyl)thiophene; 2-Iodobenzoyl Thiophene Derivative; Thiophene, 5-(1,3-dioxolan-2-yl)-2-[(2-iodophenyl)carbonyl]-; 898778-10-4; AI3-63875; CTK8G7228
EINECS	Contact for details

Quality Control

Every batch of 5-(1,3-Dioxolan-2-Yl)-2-(2-Iodobenzoyl)Thiophene is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.