Description

2-(2-Bromobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is a high-purity, advanced pharmaceutical intermediate with the CAS number 898778-01-3. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular architecture that enables targeted chemical transformations. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies for new drug discovery.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Organic Synthesis Building Block: Utilized in constructing complex heterocyclic and functionalized molecules for agrochemical and material science research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(2-Bromobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene
CAS No.	898778-01-3
Molecular Formula	C14H11BrO3S
Molecular Weight	339.21 g/mol
Synonyms	5-(1,3-Dioxolan-2-yl)-2-(2-bromobenzoyl)thiophene; 2-(2-Bromobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 2-Bromo-2'-(1,3-dioxolan-2-yl)-5'-thienyl benzophenone; Thiophene, 2-(2-bromobenzoyl)-5-(1,3-dioxolan-2-yl)-; 898778-01-3
EINECS	Contact for details

Quality Control

Our 2-(2-Bromobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.