Description

5-(1,3-Dioxolan-2-Yl)-2-(4-Fluorobenzoyl)Thiophene is a high-purity, specialized organic intermediate with a unique molecular architecture combining thiophene, benzoyl, and dioxolane functional groups. This compound is critical for advanced pharmaceutical research and fine chemical synthesis, where precise molecular control is paramount. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and fluorinated aryl ketone motifs.
• Material Science Precursor: Acts as a monomer or precursor for the synthesis of conjugated polymers and organic electronic materials for applications in OLEDs or organic photovoltaics.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, utilizing the sulfur and oxygen donor atoms within its structure.
• Chemical Biology Probe Development: Utilized as a core scaffold for creating molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	5-(1,3-Dioxolan-2-Yl)-2-(4-Fluorobenzoyl)Thiophene
CAS No.	898773-41-6
Molecular Formula	C14H11FO3S
Molecular Weight	278.30 g/mol
Synonyms	2-(4-Fluorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(4-fluorobenzoyl)thiophene; 898773-41-6; 4-Fluoro-[5-(1,3-dioxolan-2-yl)thiophen-2-yl]phenylmethanone; Thiophene, 5-(1,3-dioxolan-2-yl)-2-(4-fluorobenzoyl)-
EINECS	Contact for details

Quality Control

Every batch of 5-(1,3-Dioxolan-2-Yl)-2-(4-Fluorobenzoyl)Thiophene is produced under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.