Description

5-(1,3-Dioxolan-2-Yl)-2-(2-Fluorobenzoyl)Thiophene is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it combines a thiophene core with fluorinated benzoyl and protected aldehyde functionalities, enabling precise molecular construction for complex targets. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, leveraging the bioactivity of the thiophene and fluorine motifs.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as semiconductors and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-catalyzed cross-coupling reactions.
• Fluorescent Probe Synthesis: Utilized in the creation of fluorophores and molecular probes for biochemical sensing and imaging.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns under cGMP or ISO standards.

Basic Information

Product Name	5-(1,3-Dioxolan-2-Yl)-2-(2-Fluorobenzoyl)Thiophene
CAS No.	898773-35-8
Molecular Formula	C₁₄H₁₁FO₃S
Molecular Weight	278.30 g/mol
Synonyms	2-(2-Fluorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(2-fluorobenzoyl)thiophene; 2-Fluoro-5'-(1,3-dioxolan-2-yl)-2'-thenylphenylmethanone; Thiophene, 5-(1,3-dioxolan-2-yl)-2-(2-fluorobenzoyl)-; 898773-35-8; 2-(2-Fluorobenzoyl)thiophene-5-carboxaldehyde ethylene acetal
EINECS	Contact for details

Quality Control

Our 5-(1,3-Dioxolan-2-Yl)-2-(2-Fluorobenzoyl)Thiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.