Description

5-(1,3-Dioxolan-2-Yl)-2-(4-Trifluoromethylbenzoyl)Thiophene is a high-purity advanced pharmaceutical intermediate (API intermediate) featuring a unique thiophene-based molecular scaffold. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients, particularly those targeting specific receptor pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those with thiophene cores for therapeutic applications.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its trifluoromethyl and benzoyl functionalities.
• Material Science Precursor: Serves as a specialized monomer or precursor for organic electronic materials and functional polymers.
• Chemical Synthesis: A versatile reagent for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands for catalytic systems and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-(1,3-Dioxolan-2-Yl)-2-(4-Trifluoromethylbenzoyl)Thiophene
CAS No.	898773-32-5
Molecular Formula	C₁₅H₁₁F₃O₃S
Molecular Weight	328.31 g/mol
Synonyms	2-(4-Trifluoromethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(4-(trifluoromethyl)benzoyl)thiophene; 898773-32-5; Thiophene, 5-(1,3-dioxolan-2-yl)-2-[4-(trifluoromethyl)benzoyl]-; 2-(4-Trifluoromethylbenzoyl)-5-(dioxolanyl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(α,α,α-trifluoro-p-toluoyl)thiophene
EINECS	Contact for details

Quality Control

Our 5-(1,3-Dioxolan-2-Yl)-2-(4-Trifluoromethylbenzoyl)Thiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.