Description

5-(1,3-Dioxolan-2-Yl)-2-(3-Methoxybenzoyl)Thiophene is a high-purity, advanced pharmaceutical intermediate featuring a unique thiophene-based molecular scaffold. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel organic materials, offering a versatile building block for medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing combinatorial libraries and exploring structure-activity relationships (SAR) in lead optimization.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Organic Electronic Materials: A potential precursor for the synthesis of conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of client-specific molecules.

Basic Information

Product Name	5-(1,3-Dioxolan-2-Yl)-2-(3-Methoxybenzoyl)Thiophene
CAS No.	898773-11-0
Molecular Formula	C15H14O4S
Molecular Weight	290.33 g/mol
Synonyms	2-(3-Methoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; 5-(1,3-Dioxolan-2-yl)-2-(3-methoxybenzoyl)thiophene; 2-(3-Methoxybenzoyl)thiophene-5-carboxaldehyde ethylene acetal; Thiophene derivative CAS 898773-11-0; [898773-11-0]; 3-Methoxybenzoylthiophene derivative
EINECS	Contact for details

Quality Control

Our 5-(1,3-Dioxolan-2-Yl)-2-(3-Methoxybenzoyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.