Description

5-(1,3-Dioxolan-2-Yl)-2-Thienyl 1-Methylbutyl Ketone is a specialized organic compound featuring a thienyl ketone core protected by a dioxolane group. This unique structure makes it a valuable advanced intermediate for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where its functional groups offer strategic handles for further chemical elaboration.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the thiophene moiety is a common pharmacophore.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds and natural product analogs.
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing specific sulfur-containing aroma compounds.

Basic Information

Product Name	5-(1,3-Dioxolan-2-Yl)-2-Thienyl 1-Methylbutyl Ketone
CAS No.	898772-90-2
Molecular Formula	C13H18O3S
Molecular Weight	254.34 g/mol
Synonyms	1-(5-(1,3-Dioxolan-2-yl)thiophen-2-yl)-2-methylpentan-1-one; 2-Methyl-1-[5-(1,3-dioxolan-2-yl)-2-thienyl]-1-pentanone; 5-(1,3-Dioxolan-2-yl)thiophene-2-yl 1-methylbutyl ketone; 2-Methylpentyl 5-(1,3-dioxolan-2-yl)thiophen-2-yl ketone; 1-Methylbutyl 5-(2,2-dimethyl-1,3-dioxolan-4-yl)thiophen-2-yl ketone (related protected form); Thienyl ketone dioxolane derivative
EINECS	Contact for details

Quality Control

Our production of 5-(1,3-Dioxolan-2-Yl)-2-Thienyl 1-Methylbutyl Ketone adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.