Description

2,2-Dimethylpropyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone is a specialized organic compound featuring a thiophene core protected by a dioxolane group, making it a valuable synthetic intermediate. Its molecular architecture is engineered for high reactivity and selectivity in complex organic transformations, particularly in the synthesis of advanced pharmaceutical and agrochemical agents. This compound is essential for R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries seeking to build novel heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing thiophene or dioxolane motifs for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides, herbicides, and fungicides where the thienyl ketone structure imparts specific biological activity.
• Material Science Research: Serves as a precursor for the development of organic semiconductors, conductive polymers, and advanced functional materials due to its electron-rich thiophene unit.
• Organic Synthesis & Catalysis: Employed in academic and industrial research for constructing complex molecules, studying reaction mechanisms, and developing new catalytic methodologies.
• Ligand & Chelator Development: The ketone and heterocyclic functionalities make it a candidate for developing novel ligands in coordination chemistry and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,2-Dimethylpropyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone
CAS No.	898772-86-6
Molecular Formula	C14H20O3S
Molecular Weight	268.37 g/mol
Synonyms	5-(1,3-Dioxolan-2-yl)-2-thenoyl tert-butyl ketone; 2,2-Dimethylpropyl 5-(1,3-dioxolan-2-yl)thiophene-2-carboxylate; 5-(1,3-Dioxolan-2-yl)thiophene-2-carboxylic acid tert-butyl ester; 2-(1,3-Dioxolan-2-yl)-5-[(2,2-dimethylpropanoyl)methyl]thiophene; tert-Butyl 5-(1,3-dioxolan-2-yl)thiophene-2-carboxylate; 5-(1,3-Dioxolan-2-yl)-2-thienyl 2,2-dimethylpropyl ketone
EINECS	Contact for details

Quality Control

Our production of 2,2-Dimethylpropyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support custom purity requirements for specific R&D or scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.