Description

Cyclopropyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone is a high-purity, specialized organic building block featuring a unique heterocyclic structure that combines a thiophene ring with a ketone and a protected aldehyde functionality. This compound is of significant value in advanced pharmaceutical and agrochemical research, serving as a critical intermediate for the synthesis of novel active molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its thiophene-based scaffold.
• Material Science Research: Serves as a precursor for organic electronic materials and functional polymers due to its conjugated system.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions.
• Custom Synthesis: A starting point for the bespoke production of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Cyclopropyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone
CAS No.	898772-50-4
Molecular Formula	C11H12O3S
Molecular Weight	224.28 g/mol
Synonyms	2-Thiophenecarboxaldehyde, 5-(1,3-dioxolan-2-yl)-, cyclopropyl ketone; 5-(1,3-Dioxolan-2-yl)-2-thienyl cyclopropyl ketone; Cyclopropyl[5-(1,3-dioxolan-2-yl)-2-thienyl]methanone; 2-(5-(Cyclopropanecarbonyl)thiophen-2-yl)-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our Cyclopropyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; therefore, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.