Description

4-Chlorobutyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone is a specialized organic building block featuring a thiophene core protected by a dioxolane group and a reactive chlorobutyl ketone side chain. This compound matters as a versatile and high-purity synthetic intermediate, enabling the precise construction of complex molecules for advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D laboratories for the synthesis of novel active ingredients and by fine chemical manufacturers producing custom intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Serves as a precursor for functionalized monomers or ligands in the development of advanced polymers, conductive materials, or metal-organic frameworks (MOFs).
• Organic Synthesis & Method Development: A valuable substrate for chemists developing new catalytic reactions, cross-coupling methodologies, or studying the reactivity of protected carbonyl compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, custom fine chemicals and specialty intermediates for various industrial sectors.

Basic Information

Product Name	4-Chlorobutyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone
CAS No.	898772-47-9
Molecular Formula	C13H17ClO3S
Molecular Weight	288.79 g/mol
Synonyms	1-(5-(1,3-Dioxolan-2-yl)thiophen-2-yl)-4-chlorobutan-1-one; 4-Chloro-1-[5-(1,3-dioxolan-2-yl)-2-thienyl]-1-butanone; 4-Chlorobutyl 5-(1,3-dioxolan-2-yl)thiophen-2-yl ketone; 5-(1,3-Dioxolan-2-yl)-2-thienyl 4-chlorobutyl ketone
EINECS	Contact for details

Quality Control

Our 4-Chlorobutyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.