Description

3-Chloropropyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone is a high-value, specialized organic intermediate featuring a thiophene core protected by an acetal group. This compound matters for its role as a versatile building block in the synthesis of complex heterocyclic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, or insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the creation of advanced organic electronic materials, such as organic semiconductors or conductive polymers, due to its thiophene moiety.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic routes.
• Academic and Institutional Research: Utilized in university and government labs for fundamental studies in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	3-Chloropropyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone
CAS No.	898772-44-6
Molecular Formula	C11H13ClO3S
Molecular Weight	260.74 g/mol
Synonyms	1-[5-(1,3-Dioxolan-2-yl)thiophen-2-yl]-3-chloropropan-1-one; 3-Chloro-1-[5-(1,3-dioxolan-2-yl)-2-thienyl]-1-propanone; 3-Chloro-1-(5-(1,3-dioxolan-2-yl)thiophen-2-yl)propan-1-one; 5-(1,3-Dioxolan-2-yl)-2-thienyl 3-chloropropyl ketone; 2-Thienyl ketone, 3-chloropropyl 5-(1,3-dioxolan-2-yl)-; Acetal-protected thiophene ketone intermediate
EINECS	Contact for details

Quality Control

Our 3-Chloropropyl 5-(1,3-Dioxolan-2-Yl)-2-Thienyl Ketone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. For custom synthesis projects, we adhere to cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.