Description

Ethyl 5-(1,3-Dioxolan-2-Yl)-2-Thenoylformate is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing new generation pesticides and herbicides with enhanced efficacy and selectivity.
• Organic Synthesis & Research: Used in academic and industrial R&D laboratories for constructing complex thiophene and dioxolane-containing molecular frameworks.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including dyes, pigments, and functional materials requiring specific heterocyclic motifs.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for target molecules in pilot plants and commercial production.

Basic Information

Product Name	Ethyl 5-(1,3-Dioxolan-2-Yl)-2-Thenoylformate
CAS No.	898772-32-2
Molecular Formula	C₁₂H₁₄O₅S
Molecular Weight	270.30 g/mol
Synonyms	Ethyl 5-(1,3-dioxolan-2-yl)thiophene-2-carboxylate; 2-Thenoylformic Acid Ethyl Ester, 5-(1,3-Dioxolan-2-yl) Derivative; 5-(1,3-Dioxolan-2-yl)thiophene-2-carboxylic Acid Ethyl Ester; Ethyl 5-(2,2-Dimethyl-1,3-dioxolan-4-yl)thiophene-2-carboxylate (related); Thiophene-2-carboxylic acid, 5-(1,3-dioxolan-2-yl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-(1,3-Dioxolan-2-Yl)-2-Thenoylformate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.