Description

Butyl 5-(1,3-Dioxolan-2-Yl)-2-Thiophenecarboxylate is a specialized organic building block featuring a thiophene core protected by a dioxolane group. This compound is valued for its role as a key synthetic intermediate in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic structures.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where the thiophene moiety can impart specific biological activity.
• Material Science Research: Acts as a monomer or functionalized unit in the development of conductive polymers, organic semiconductors, and other advanced electronic materials.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules, leveraging the reactivity of the carboxylate ester and the masked aldehyde of the dioxolane group.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.

Basic Information

Product Name	Butyl 5-(1,3-Dioxolan-2-Yl)-2-Thiophenecarboxylate
CAS No.	898772-14-0
Molecular Formula	C14H18O4S
Molecular Weight	282.35 g/mol
Synonyms	2-Thiophenecarboxylic acid, 5-(1,3-dioxolan-2-yl)-, butyl ester; Butyl 5-(1,3-dioxolan-2-yl)thiophene-2-carboxylate; 5-(1,3-Dioxolan-2-yl)thiophene-2-carboxylic acid butyl ester; Thiophene-2-carboxylic acid, 5-(1,3-dioxolan-2-yl)-, butyl ester; Butyl 5-(2,2-dimethyl-1,3-dioxolan-4-yl)thiophene-2-carboxylate (related protected form); BDTC
EINECS	Contact for details

Quality Control

Our Butyl 5-(1,3-Dioxolan-2-Yl)-2-Thiophenecarboxylate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.