Description

Ethyl 5-(1,3-Dioxolan-2-Yl)-2-Thiophenecarboxylate is a high-purity, specialized organic compound featuring a thiophene core protected by a dioxolane group. This molecule serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with thiophene-based heterocyclic structures.
• Agrochemical Synthesis: Building block for developing new generation pesticides, herbicides, and fungicides.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and other functional electronic materials.
• Organic Synthesis: Versatile reagent for constructing complex molecules in medicinal chemistry and process research.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for method development and exploration of new chemical entities.

Basic Information

Product Name	Ethyl 5-(1,3-Dioxolan-2-Yl)-2-Thiophenecarboxylate
CAS No.	898772-08-2
Molecular Formula	C10H12O4S
Molecular Weight	228.27 g/mol
Synonyms	Ethyl 5-(1,3-dioxolan-2-yl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 5-(1,3-dioxolan-2-yl)-, ethyl ester; Ethyl 5-(2,2-Dimethyl-1,3-dioxolan-4-yl)thiophene-2-carboxylate (related protected form); Thiophene-2-carboxylic acid ethyl ester derivative; 898772-08-2; 5-(1,3-Dioxolan-2-yl)thiophene-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-(1,3-Dioxolan-2-Yl)-2-Thiophenecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.