Description

3-(3,4-Difluorobenzoyl)Thiophene is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the difluorobenzoyl-thiophene scaffold imparts desirable biological and physicochemical properties. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging the bioactivity of the fluorinated aromatic system.
• Material Science Research: Serves as a precursor for organic electronic materials, such as semiconductors and light-emitting materials, due to the thiophene moiety.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating novel ligands used in catalytic processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Academic and R&D Laboratories: Utilized in fundamental organic chemistry research and for exploring new synthetic methodologies.

Basic Information

Product Name	3-(3,4-Difluorobenzoyl)Thiophene
CAS No.	898771-62-5
Molecular Formula	C11H6F2OS
Molecular Weight	224.23 g/mol
Synonyms	3-(3,4-Difluorobenzoyl)thiophene; Thiophene, 3-(3,4-difluorobenzoyl)-; 3,4-Difluorophenyl 3-thienyl ketone; 3-(3,4-Difluorophenyl)-3-thienylmethanone; 3-Thienyl 3,4-difluorophenyl ketone; 898771-62-5; 3-(3,4-Difluorobenzoyl)-thiophene
EINECS	Contact for details

Quality Control

Our 3-(3,4-Difluorobenzoyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical-grade applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.