Description

3-(2-Chloro-4-Fluorobenzoyl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated benzoyl-thiophene structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its precise molecular architecture enables targeted drug development. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for creating novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs.
• API Synthesis: Serves as a crucial building block for the production of complex Active Pharmaceutical Ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive thiophene core.
• Material Science Precursor: Acts as a starting material for the synthesis of specialized organic compounds used in electronic materials and functional polymers.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis and process development for clients.

Basic Information

Product Name	3-(2-Chloro-4-Fluorobenzoyl)Thiophene
CAS No.	898771-41-0
Molecular Formula	C11H6ClFOS
Molecular Weight	240.68 g/mol
Synonyms	2-Chloro-4-fluoro-3-thienyl phenyl ketone; (2-Chloro-4-fluorophenyl)(thiophen-3-yl)methanone; 3-(2-Chloro-4-fluorobenzoyl)thiophene; 898771-41-0; Thiophene, 3-(2-chloro-4-fluorobenzoyl)-; Methanone, (2-chloro-4-fluorophenyl)-3-thienyl-
EINECS	Contact for details

Quality Control

Our 3-(2-Chloro-4-Fluorobenzoyl)Thiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.