Description

3-(4-Bromo-2-Fluorobenzoyl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated benzoyl-thiophene structure. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides and fungicides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors and functional materials due to the electron-rich thiophene moiety.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring halogenated aromatic ketones.
• Academic & Industrial R&D: Employed in exploratory chemistry for creating new chemical entities with potential biological activity.

Basic Information

Product Name	3-(4-Bromo-2-Fluorobenzoyl)Thiophene
CAS No.	898771-38-5
Molecular Formula	C11H6BrFO1S
Molecular Weight	285.13 g/mol
Synonyms	4-Bromo-2-fluoro-3-thienyl phenyl ketone; (4-Bromo-2-fluorophenyl)(thiophen-3-yl)methanone; 3-(4-Bromo-2-fluorobenzoyl)thiophene; Thiophene, 3-[(4-bromo-2-fluorophenyl)carbonyl]-; 898771-38-5; 3-(4-Bromo-2-fluoro-benzoyl)-thiophene
EINECS	Contact for details

Quality Control

Our 3-(4-Bromo-2-Fluorobenzoyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.