Description

2-Chloro-4-(Trifluoromethyl)Benzothiazole is a high-value, multi-functional heterocyclic building block characterized by its benzothiazole core substituted with chloro and trifluoromethyl groups. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique electronic and steric properties are leveraged. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, including ligands for catalysts and components for organic light-emitting diodes (OLEDs).
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of specialized dyes and fluorescent markers.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for bespoke chemical synthesis and scale-up projects.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethyl)Benzothiazole
CAS No.	898748-15-7
Molecular Formula	C8H3ClF3NS
Molecular Weight	237.63 g/mol
Synonyms	2-Chloro-4-(trifluoromethyl)-1,3-benzothiazole; 4-(Trifluoromethyl)-2-chlorobenzothiazole; 2-Chloro-4-trifluoromethylbenzothiazole; Benzothiazole, 2-chloro-4-(trifluoromethyl)-; 898748-15-7; 2-Chloro-4-(trifluoromethyl)benzothiazole; 2-Chloro-4-(trifluoromethyl)-benzothiazole
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Trifluoromethyl)Benzothiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.