Description

4-Bromo-6-Cyanoindazole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both bromo and cyano substituents on the indazole core, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other biologically active small molecules.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical assays.
• Cross-Coupling Reactions: The bromo substituent is an excellent handle for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations.
• Nucleophilic Substitution & Functionalization: The cyano group can be hydrolyzed, reduced, or serve as a precursor to tetrazoles and other heterocycles.

Basic Information

Product Name	4-Bromo-6-Cyanoindazole
CAS No.	898746-96-8
Molecular Formula	C8H4BrN3
Molecular Weight	222.04 g/mol
Synonyms	4-Bromo-1H-indazole-6-carbonitrile; 6-Cyano-4-bromo-1H-indazole; 4-Bromo-6-cyano-1H-indazole; 1H-Indazole-6-carbonitrile, 4-bromo-; 898746-96-8; 4-Bromoindazole-6-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Cyanoindazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.