Description

n-Boc-5-Methoxytryptophol is a protected indole derivative, specifically a tryptophol analog, that serves as a crucial synthetic intermediate in advanced organic synthesis. Its value lies in the Boc (tert-butoxycarbonyl) protecting group, which safeguards the amine functionality, allowing for selective reactions elsewhere on the molecule during complex multi-step sequences. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex molecules, including potential drug candidates with indole-based structures.
• Peptidomimetic Research: Used to incorporate modified tryptophan analogs into peptide chains for studying structure-activity relationships.
• Medicinal Chemistry: Serves as a precursor for the development of serotonin receptor modulators and other neurologically active compounds.
• Organic Synthesis: Employed in multi-step synthetic routes where selective protection and deprotection strategies are required.
• Bioconjugation Chemistry: Potential use in creating labeled probes or conjugates for biochemical research, leveraging the hydroxyl and protected amine groups.
• Academic Research: A valuable reagent for methodology development and the total synthesis of natural products containing indole motifs.

Basic Information

Product Name	n-Boc-5-Methoxytryptophol
CAS No.	898746-70-8
Molecular Formula	C₁₇H₂₃NO₄
Molecular Weight	305.37 g/mol
Synonyms	tert-Butyl (2-(5-methoxy-1H-indol-3-yl)ethyl)carbamate; 5-Methoxytryptophol N-Boc derivative; 2-(5-Methoxy-1H-indol-3-yl)ethan-1-ol, N-Boc protected; Boc-5-MeO-Tryptophol; N-(tert-Butoxycarbonyl)-5-methoxytryptophol; 3-(2-((tert-Butoxycarbonyl)amino)ethyl)-5-methoxyindole; 5-Methoxy-N-Boc-tryptophol
EINECS	Contact for details

Quality Control

Our n-Boc-5-Methoxytryptophol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.