Description

n-Boc-5-Chlorotryptophol is a protected indole derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and versatile synthetic intermediate for the development of complex pharmaceutical molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those containing a functionalized tryptamine or tryptophan core.
• Peptidomimetic Research: Used in the design and construction of non-peptide compounds that mimic the structure and function of peptides, relevant for drug discovery.
• Alkaloid Synthesis: Serves as a starting material or intermediate for the laboratory-scale synthesis of natural product analogs and complex heterocyclic alkaloids.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic activity.
• Bioconjugation & Probe Development: The protected amine and hydroxyl groups provide handles for further chemical modification, useful in creating biochemical probes.

Basic Information

Product Name	n-Boc-5-Chlorotryptophol
CAS No.	898746-66-2
Molecular Formula	C₁₅H₁₈ClNO₃
Molecular Weight	295.76 g/mol
Synonyms	tert-Butyl (5-chloro-1H-indol-3-yl)(2-hydroxyethyl)carbamate; 5-Chloro-3-[2-[(tert-butoxycarbonyl)amino]ethyl]-1H-indole; 1H-Indole-3-ethanol, 5-chloro-β-[[(1,1-dimethylethoxy)carbonyl]amino]-; Boc-5-Chloro-Trp-ol; N-Boc-5-Chlorotryptamine Alcohol; (5-Chloro-1H-indol-3-yl)-[2-(tert-butoxycarbonylamino)-ethyl]carbinol
EINECS	Contact for details

Quality Control

Our n-Boc-5-Chlorotryptophol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.