Description

6-Azaindole-3-Carboxaldehyde is a versatile and high-value heterocyclic building block, specifically a functionalized azaindole derivative. This compound is critical for medicinal chemistry research and pharmaceutical development due to its role as a key precursor in synthesizing complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors to create novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial scaffold for the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Acts as a building block for creating novel active ingredients with herbicidal or insecticidal properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: Potential precursor for organic electronic materials and ligands in catalytic systems.

Basic Information

Product Name	6-Azaindole-3-Carboxaldehyde
CAS No.	898746-46-8
Molecular Formula	C8H6N2O
Molecular Weight	146.15 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde; 1H-Pyrrolo[2,3-b]pyridine-3-carbaldehyde; 3-Formyl-1H-pyrrolo[2,3-b]pyridine; 6-Aza-1H-indole-3-carboxaldehyde; 6-Azaindole-3-aldehyde; 3-Aldehyde-6-azaindole
EINECS	Contact for details

Quality Control

Our 6-Azaindole-3-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized and light-sensitive. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.