Description

Tetrahydro-2H-Pyran-2-Yl 2,3,4,6-Tetra-o-Acetyl-5-Thio-D-Glucopyranose is a sophisticated thioglycoside derivative, serving as a crucial protected intermediate in synthetic carbohydrate chemistry. Its primary value lies in enabling the controlled synthesis of complex oligosaccharides and glycoconjugates, which are essential for pharmaceutical and biochemical research. This high-purity building block is particularly vital for R&D teams and process chemists in the pharmaceutical, biotechnology, and agrochemical sectors who are developing novel therapeutics, diagnostic tools, and bioactive compounds.

Application

• Glycosylation Reagent: A key building block for the stereoselective synthesis of S-linked oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, including antiviral, anticancer, and anti-inflammatory agents.
• Glycobiology Research: Essential for studying carbohydrate-protein interactions and developing glycan-based probes and inhibitors.
• Carbohydrate Mimetic Synthesis: Facilitates the creation of thio-sugar analogs with enhanced metabolic stability for biological evaluation.
• Agrochemical Development: Employed in synthesizing advanced, bioactive carbohydrate derivatives for crop protection.
• Process Chemistry: Serves as a stable, protected intermediate for scalable manufacturing processes in fine chemical production.

Basic Information

Product Name	Tetrahydro-2H-Pyran-2-Yl 2,3,4,6-Tetra-o-Acetyl-5-Thio-D-Glucopyranose
CAS No.	898538-14-2
Molecular Formula	C19H28O10S
Molecular Weight	448.49 g/mol
Synonyms	5-Thio-D-glucopyranose, 1,2,3,4-tetra-O-acetyl-5-thio-α-D-, 2-(tetrahydro-2H-pyran-2-yl) thioacetate; 2,3,4,6-Tetra-O-acetyl-5-thio-α-D-glucopyranosyl 2-(tetrahydro-2H-pyran-2-yl) sulfide; 5-Thio-α-D-glucopyranose, 1,2,3,4-tetraacetate, 5-[2-(tetrahydro-2H-pyran-2-yl)thio]acetate; THP-protected 5-thio-D-glucose tetraacetate; 1,2,3,4-Tetra-O-acetyl-5-thio-α-D-glucopyranose THP derivative; 5-Thio-D-glucose tetraacetate THP ether.
EINECS	Contact for details

Quality Control

Our Tetrahydro-2H-Pyran-2-Yl 2,3,4,6-Tetra-o-Acetyl-5-Thio-D-Glucopyranose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.