Description

5-[(2-Chloroethyl)(2-Hydroxyethyl)Amino]-1-Methyl-1H-Benzimidazole-2-Butanoic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories focused on developing new drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel benzimidazole-derived active pharmaceutical ingredients (APIs).
• Oncology Drug Research: Used in the development of potential anti-cancer agents due to its specific functionalized benzimidazole core.
• Medicinal Chemistry R&D: Serves as a crucial precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Employed by fine chemical manufacturers for the contract synthesis of complex molecules for clinical trials.
• Biochemical Research: May be used as a tool compound or a precursor for labeled analogs in biochemical and pharmacological studies.

Basic Information

Item	Details
Product Name	5-[(2-Chloroethyl)(2-Hydroxyethyl)Amino]-1-Methyl-1H-Benzimidazole-2-Butanoic Acid Ethyl Ester
CAS No.	898224-95-8
Molecular Formula	C18H26ClN3O3
Molecular Weight	367.87 g/mol
Synonyms	Ethyl 5-[(2-Chloroethyl)(2-Hydroxyethyl)Amino]-1-Methyl-1H-Benzimidazole-2-Butanoate; 5-[(2-Chloroethyl)(2-Hydroxyethyl)Amino]-1-Methyl-1H-Benzimidazole-2-Butanoic Acid Ethyl Ester; Benzimidazole Butanoic Acid Ethyl Ester Derivative; 898224-95-8; 1-Methyl-5-[N-(2-chloroethyl)-N-(2-hydroxyethyl)amino]-1H-benzimidazole-2-butanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 5-[(2-Chloroethyl)(2-Hydroxyethyl)Amino]-1-Methyl-1H-Benzimidazole-2-Butanoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.