Description

6-Bromo-1-Methylindolin-2-One is a high-purity, versatile brominated indolinone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized core structure for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its modifiable bromine and carbonyl functionalities.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients in crop protection and pest management products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	6-Bromo-1-Methylindolin-2-One
CAS No.	897957-06-1
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	6-Bromo-1-methylindolin-2-one; 6-Bromo-1-methyl-2-indolinone; 1-Methyl-6-bromoindolin-2-one; 2-Indolinone, 6-bromo-1-methyl-; 6-Bromo-1-methyl-1,3-dihydro-2H-indol-2-one; 6-Bromo-N-methylisatin; 897957-06-1
EINECS	Contact for details

Quality Control

Our 6-Bromo-1-Methylindolin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for the production of pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.