Description

2,3(1H)-Isoquinolinedicarboxylic Acid, 6-Borono-3,4-Dihydro-, 2-(1,1-Dimethylethyl) 3-Methyl Ester is a high-value, synthetically advanced boronic acid ester derivative. This compound is a critical pharmaceutical intermediate and building block in modern organic synthesis, prized for its unique functional groups that enable complex molecular transformations. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for complex molecules targeting specific disease pathways.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester coupling partner for constructing biaryl and other carbon-carbon bonds, a cornerstone of modern medicinal chemistry.
• Protease Inhibitor Research: Used in the development and screening of protease inhibitors, leveraging the isoquinoline scaffold's bioactivity.
• Chemical Biology & Drug Discovery: Employed as a molecular probe or building block in high-throughput screening and the creation of targeted compound libraries.
• Advanced Material Synthesis: Potential use in creating organic electronic materials or complex ligands for catalytic systems due to its conjugated structure.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploratory synthesis projects.

Basic Information

Product Name	2,3(1H)-Isoquinolinedicarboxylic Acid, 6-Borono-3,4-Dihydro-, 2-(1,1-Dimethylethyl) 3-Methyl Ester
CAS No.	897375-70-1
Molecular Formula	C17H20BNO6
Molecular Weight	345.16 g/mol
Synonyms	6-Borono-3,4-dihydro-2,3(1H)-isoquinolinedicarboxylic acid 2-tert-butyl 3-methyl ester; 2-(tert-Butyl) 3-methyl 6-borono-3,4-dihydro-1H-isoquinoline-2,3-dicarboxylate; tert-Butyl methyl 6-borono-3,4-dihydroisoquinoline-2,3-dicarboxylate; Boronic Acid Ester of Dihydroisoquinoline; CAS 897375-70-1; BRN 897375-70-1; Pharmaceutical Intermediate 897375-70-1
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity against established specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our manufacturing and quality processes are designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or with appropriate desiccants to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.