Description

(S)-1-(4-Methoxyphenyl)-2'-((R)-1-(4-Methoxyphenyl)-3,3-Dimethyl-4-Oxoazetidin-2-Yloxy)-3,3-Dimethylspiro[Azetidine-2,3'-Indol]-4-One is a high-purity, complex spirocyclic organic compound featuring a unique azetidine-indole fused structure. This compound is of significant interest as a key chiral intermediate or building block in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly those targeting central nervous system disorders or requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of potential drug candidates, especially for neurological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new bioactive molecules.
• Asymmetric Synthesis: Employed as a substrate or template in catalytic asymmetric reactions due to its defined stereocenters.
• Process Chemistry Development: Acts as a reference standard or key material during the scale-up and optimization of synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Can be utilized in the development of molecular probes to study biological pathways and protein interactions.
• Academic Research: Used in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(S)-1-(4-Methoxyphenyl)-2'-((R)-1-(4-Methoxyphenyl)-3,3-Dimethyl-4-Oxoazetidin-2-Yloxy)-3,3-Dimethylspiro[Azetidine-2,3'-Indol]-4-One
CAS No.	896746-39-7
Molecular Formula	C31H31N3O5
Molecular Weight	525.60 g/mol
Synonyms	896746-39-7; Spiro[azetidine-2,3'-indol]-4-one, (S)-1-(4-methoxyphenyl)-2'-[(R)-1-(4-methoxyphenyl)-3,3-dimethyl-4-oxo-2-azetidinyl]oxy]-3,3-dimethyl-; (S)-1-(4-Methoxyphenyl)-2'-((R)-1-(4-methoxyphenyl)-3,3-dimethyl-4-oxoazetidin-2-yloxy)-3,3-dimethylspiro[azetidine-2,3'-indol]-4-one; 2'-[(2R)-1-(4-Methoxyphenyl)-3,3-dimethyl-4-oxo-2-azetidinyl]oxy]-3,3-dimethyl-(2S)-1-(4-methoxyphenyl)spiro[azetidine-2,3'-indol]-4-one; Azetidine-Indole Spirocycle Derivative; Light-sensitive Spirocyclic Intermediate
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Our quality system includes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.