Description

1-(Phenylsulphonyl)-6-Methyl-7-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel, small-molecule drug candidates, particularly in oncology and other therapeutic areas. It is primarily required by research institutions, contract research and manufacturing organizations (CROs/CMOs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point for creating compound libraries in drug discovery programs.
• Kinase Inhibitor Development: The azaindole structure is prevalent in the design of potent and selective kinase inhibitors for targeted cancer therapies.
• Process Chemistry & Scale-up: Employed in route scouting, optimization, and pilot-scale synthesis for clinical trial material production.
• Biochemical Research: May be used as a tool compound or ligand in biochemical assays and target validation studies.

Basic Information

Product Name	1-(Phenylsulphonyl)-6-Methyl-7-Azaindole
CAS No.	896722-51-3
Molecular Formula	C16H14N2O2S
Molecular Weight	298.36 g/mol
Synonyms	6-Methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-methyl-1-(phenylsulfonyl)-; 6-Methyl-1-(phenylsulfonyl)-7-azaindole; 1-Benzenesulfonyl-6-methyl-1H-pyrrolo[2,3-b]pyridine; 6-Methyl-1-tosyl-7-azaindole (common misnomer); 1-(Phenylsulfonyl)-6-methyl-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulphonyl)-6-Methyl-7-Azaindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.