Description

5-(Piperidin-1-Ylmethyl)Thiophene-2-Carboxylic Acid is a high-value heterocyclic carboxylic acid building block, pivotal for advanced pharmaceutical and agrochemical research. Its molecular architecture, featuring a thiophene core linked to a piperidine moiety via a methylene bridge, makes it an essential intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and GPCR modulators.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker in the development of chemical probes, enzyme inhibitors, and molecular tools for biological research.
• Material Science Research: Employed as a monomer or functional additive in the synthesis of conductive polymers, organic semiconductors, and advanced polymeric materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-(Piperidin-1-Ylmethyl)Thiophene-2-Carboxylic Acid
CAS No.	893741-64-5
Molecular Formula	C12H15NO2S
Molecular Weight	237.32 g/mol
Synonyms	5-[(Piperidin-1-yl)methyl]thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-[(1-piperidinyl)methyl]-; 5-(Piperidin-1-ylmethyl)thiophene-2-carboxylic acid; 5-(1-Piperidinylmethyl)-2-thiophenecarboxylic acid; Thiophene-2-carboxylic acid, 5-(piperidin-1-ylmethyl)-; 893741-64-5; 5-Piperidin-1-ylmethyl-thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(Piperidin-1-Ylmethyl)Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.