Description

5-(3-Fluorophenyl)Thiophene-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate unique fluorinated thiophene motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorophenyl-thiophene scaffold imparts desired biological activity and metabolic stability.
• Material Science: Serves as a monomer or building block for creating specialized polymers, organic semiconductors, and liquid crystals with tailored electronic and optical properties.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag due to the distinctive spectroscopic signature of the fluorine atom and thiophene ring.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	5-(3-Fluorophenyl)Thiophene-2-Carboxylic Acid
CAS No.	893733-12-5
Molecular Formula	C11H7FO2S
Molecular Weight	222.24 g/mol
Synonyms	5-(3-Fluorophenyl)-2-thiophenecarboxylic acid; 2-Thiophenecarboxylic acid, 5-(3-fluorophenyl)-; 3-Fluoro-5-(thiophen-2-yl)benzoic acid (tautomeric form); 5-(m-Fluorophenyl)thiophene-2-carboxylic acid; 893733-12-5; 5-(3-Fluorophenyl)-2-thiophenecarboxylic acid; 5-(3-Fluorophenyl)thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5-(3-Fluorophenyl)Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.