Description

2(1H)-Isoquinolinecarboxylic Acid, 3,4-Dihydro-8-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, 1,1-Dimethylethyl Ester CAS NO 893566-73-9 is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is specifically engineered for use in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl structures. It is an essential building block for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality precursors for drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of active pharmaceutical ingredients (APIs) targeting a wide range of therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds between aromatic rings, enabling the construction of complex, drug-like molecules in medicinal chemistry.
• Agrochemical Research: Serves as a key precursor in the development of novel herbicides, fungicides, and insecticides.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and emissive materials for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Utilized in creating molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental research and custom synthesis projects.

Basic Information

Product Name	2(1H)-Isoquinolinecarboxylic Acid, 3,4-Dihydro-8-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, 1,1-Dimethylethyl Ester
CAS No.	893566-73-9
Molecular Formula	C20H28BNO4
Molecular Weight	357.26 g/mol
Synonyms	tert-Butyl 8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate; 1,1-Dimethylethyl 3,4-dihydro-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-isoquinolinecarboxylate; 8-Boc-3,4-dihydroisoquinoline boronic acid pinacol ester; BOC-DHIQ-Bpin; 893566-73-9
EINECS	Contact for details

Quality Control

Our 2(1H)-Isoquinolinecarboxylic Acid, 3,4-Dihydro-8-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.