Description

[4-(Tetrahydropyran-4-Yloxy)Phenyl]Methanol is a versatile organic building block characterized by its phenylmethanol core linked to a tetrahydropyranyl ether moiety. This compound matters for its role as a key chiral intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting central nervous system disorders. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals. The compound, with CAS number 892501-95-0, offers a critical structural handle for further functionalization in multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex molecular architectures via ether and alcohol functional group transformations.
• Ligand and Catalyst Development: Acts as a precursor for ligands used in asymmetric catalysis, enhancing the enantioselectivity of synthetic reactions.
• Material Science Research: Investigated as a monomer or modifying agent for specialty polymers with potential advanced material properties.
• Agrochemical Synthesis: Employed in the research and development of new generation crop protection agents and herbicides.

Basic Information

Item	Details
Product Name	[4-(Tetrahydropyran-4-Yloxy)Phenyl]Methanol
CAS No.	892501-95-0
Molecular Formula	C12H16O3
Molecular Weight	208.25 g/mol
Synonyms	4-[(Oxan-4-yl)oxy]benzenemethanol; (4-((Tetrahydro-2H-pyran-4-yl)oxy)phenyl)methanol; 4-(Tetrahydro-2H-pyran-4-yloxy)benzyl alcohol; [4-(Oxan-4-yloxy)phenyl]methanol; 892501-95-0; 4-(Tetrahydropyran-4-yloxy)benzyl alcohol
EINECS	Contact for details

Quality Control

Our [4-(Tetrahydropyran-4-Yloxy)Phenyl]Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.