Description

1H-Pyrrolo[2,3-B]Pyridine, 3-(Trifluoromethyl)-,7-Oxide is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure and trifluoromethyl group. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted bioactivity. Research and development teams in the global pharmaceutical and agrochemical industries require this precise chemical building block to accelerate their drug discovery and process optimization programs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of new generation pesticides and herbicides, leveraging the biological activity of the pyrrolopyridine scaffold.
• Material Science: Serves as a precursor for organic electronic materials and ligands in catalytic systems due to its electron-deficient aromatic system.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) focusing on heterocyclic chemistry.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the commercial manufacturing of complex molecules.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 3-(Trifluoromethyl)-,7-Oxide
CAS No.	892414-48-1
Molecular Formula	C8H5F3N2O
Molecular Weight	202.13 g/mol
Synonyms	3-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine 7-oxide; 3-(Trifluoromethyl)-7-oxo-7H-pyrrolo[2,3-b]pyridine; 3-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine N-oxide; 1H-Pyrrolo[2,3-b]pyridine, 3-(trifluoromethyl)-, 7-oxide; 892414-48-1; 7-Oxide-3-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrolo[2,3-B]Pyridine, 3-(Trifluoromethyl)-,7-Oxide is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specified parameters. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.