Description

2-(Methoxy-D3)-Bromobenzene is a deuterated aromatic compound where three hydrogen atoms on the methoxy group are replaced by deuterium. This isotopic labeling is critical for creating internal standards in analytical chemistry, enhancing the precision and reliability of mass spectrometry and NMR studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for drug metabolism studies, quantitative analysis, and the development of novel deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for LC-MS/MS: Serves as a stable, non-interfering reference compound for the accurate quantification of bromobenzene derivatives and metabolites in complex biological matrices.
• Pharmaceutical Research & Development: Used as a key synthetic intermediate and tracer in the development of deuterated drug candidates, leveraging the kinetic isotope effect for improved metabolic stability.
• Metabolite Identification & Pathway Studies: Enables precise tracking and identification of metabolites in pharmacokinetic and toxicological studies.
• NMR Spectroscopy Solvent & Reagent: Acts as a useful deuterated reagent or shift reference in nuclear magnetic resonance spectroscopy due to its distinct spectral properties.
• Agrochemical Analysis: Employed in environmental and residue analysis for brominated compounds used in crop protection.
• Chemical Synthesis Building Block: Functions as a versatile aryl halide precursor for cross-coupling reactions (e.g., Suzuki, Heck) in the synthesis of more complex, labeled organic molecules.

Basic Information

Product Name	2-(Methoxy-D3)-Bromobenzene
CAS No.	892397-56-7
Molecular Formula	C7H4D3BrO
Molecular Weight	190.04 g/mol
Synonyms	1-Bromo-2-(methoxy-d3)benzene; 2-Bromoanisole-d3; (2-Bromophenyl)(methoxy-d3) ether; o-Bromoanisole-d3; Bromobenzene, 2-methoxy-d3-; Deuterated o-Bromoanisole; 2-Methoxy-d3-bromobenzene; Methoxy-d3-labeled 2-Bromobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-(Methoxy-D3)-Bromobenzene is manufactured and tested under strict quality management protocols to ensure exceptional isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards for research and development. Certificates of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and identity confirmation are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR / NMR)	Conforms to structure
Purity (GC / HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0% (by MS or NMR)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.