Description

6-Bromo-3-Fluoroisoquinoline is a high-value halogenated isoquinoline derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where the isoquinoline core contributes to charge transport properties.
• Ligand and Catalyst Development: Serves as a scaffold for designing novel ligands in transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized as a versatile handle for bioconjugation and the development of fluorescent or bioactive probes for target identification.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-Bromo-3-Fluoroisoquinoline
CAS No.	891785-30-1
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	3-Fluoro-6-bromoisoquinoline; 6-Bromo-3-fluoro-isoquinoline; Isoquinoline, 6-bromo-3-fluoro-; 891785-30-1; 6-Br-3-F-IQ; 3-Fluoro-6-bromoisoquinoline; 6-Bromo-3-fluoroisoquinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Fluoroisoquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.