Description

1-Methoxy-6-Bromoisoquinoline is a versatile brominated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the bromine atom offers a site for cross-coupling reactions and the methoxy group provides electronic modulation, making it indispensable for constructing complex molecular architectures. This high-purity intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology and CNS research.
• Agrochemical Development: Used to create novel herbicides and pesticides by acting as a core scaffold for bioactive molecules.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors and luminescent materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential for medicinal chemistry programs and discovery chemistry in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	1-Methoxy-6-Bromoisoquinoline
CAS No.	891785-23-2
Molecular Formula	C₁₀H₈BrNO
Molecular Weight	238.08 g/mol
Synonyms	6-Bromo-1-methoxyisoquinoline; 1-Methoxy-6-bromoisoquinoline; Isoquinoline, 6-bromo-1-methoxy-; 6-Bromo-1-isoquinolinyl methyl ether; 891785-23-2
EINECS	Contact for details

Quality Control

Our 1-Methoxy-6-Bromoisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.