Description

3-[4-(1-Methylethyl)Phenyl]Imidazo[2,1-B]Thiazole-6-Carboxylic Acid is a high-purity organic intermediate belonging to the imidazothiazole class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique fused-ring structure imparts specific biological activity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides, fungicides, or insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, ligands for catalysis, or specialty polymers due to its electron-rich heterocyclic system.
• Biochemical Probe Development: Employed in medicinal chemistry to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	3-[4-(1-Methylethyl)Phenyl]Imidazo[2,1-B]Thiazole-6-Carboxylic Acid
CAS No.	891770-78-8
Molecular Formula	C15H14N2O2S
Molecular Weight	286.35 g/mol
Synonyms	3-(4-Isopropylphenyl)imidazo[2,1-b]thiazole-6-carboxylic acid; 3-(p-Cumenyl)imidazo[2,1-b]thiazole-6-carboxylic acid; 3-(4-(1-Methylethyl)phenyl)imidazo[2,1-b]thiazole-6-carboxylic acid; Imidazo[2,1-b]thiazole-6-carboxylic acid, 3-[4-(1-methylethyl)phenyl]-; 891770-78-8; 3-(4-Isopropylphenyl)-6-carboxyimidazo[2,1-b]thiazole
EINECS	Contact for details

Quality Control

Our production of 3-[4-(1-Methylethyl)Phenyl]Imidazo[2,1-B]Thiazole-6-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements, including ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.