Description

3-(4-Fluorophenyl)Imidazo[2,1-B]Thiazole-6-Carboxylic Acid is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fused imidazothiazole core imparts specific biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new small molecule therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in oncology, anti-infective, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the imidazothiazole scaffold.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways in academic and industrial research.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or organic electronic materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity fluorinated heterocycles.

Basic Information

Product Name	3-(4-Fluorophenyl)Imidazo[2,1-B]Thiazole-6-Carboxylic Acid
CAS No.	891770-32-4
Molecular Formula	C12H7FN2O2S
Molecular Weight	262.26 g/mol
Synonyms	3-(4-Fluorophenyl)imidazo[2,1-b][1,3]thiazole-6-carboxylic acid; 6-Carboxy-3-(4-fluorophenyl)imidazo[2,1-b]thiazole; Imidazo[2,1-b]thiazole-6-carboxylic acid, 3-(4-fluorophenyl)-; 3-(p-Fluorophenyl)imidazo[2,1-b]thiazole-6-carboxylic acid; CAS 891770-32-4; 3-(4-Fluorophenyl)-6-imidazo[2,1-b]thiazolecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)Imidazo[2,1-B]Thiazole-6-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP (current Good Manufacturing Practice) standards for early-phase pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.