Description

4-Methoxy-2-Piperazin-1-Yl-1,3-Benzothiazole is a high-purity, advanced pharmaceutical intermediate with a distinct benzothiazole core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists to explore structure-activity relationships (SAR) and develop new chemical entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs that incorporate the benzothiazole-piperazine pharmacophore.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard in pharmacological studies to investigate specific biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	4-Methoxy-2-Piperazin-1-Yl-1,3-Benzothiazole
CAS No.	890927-66-9
Molecular Formula	C12H15N3OS
Molecular Weight	249.33 g/mol
Synonyms	4-Methoxy-2-(piperazin-1-yl)-1,3-benzothiazole; 2-(1-Piperazinyl)-4-methoxybenzothiazole; 4-Methoxy-2-piperazinylbenzothiazole; 890927-66-9; 4-Methoxy-2-(piperazin-1-yl)benzo[d]thiazole; 2-Piperazin-1-yl-4-methoxy-1,3-benzothiazole
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-Piperazin-1-Yl-1,3-Benzothiazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.