Description

4-Methyl-5-Thiophen-2-Yl-2H-Pyrazole-3-Carboxylic Acid CAS NO 890621-27-9 is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Employed in the research and development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its fused thiophene-pyrazole structure.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.
• Academic & Institutional Research: Supports fundamental research in heterocyclic chemistry and medicinal chemistry at universities and government research institutes.

Basic Information

Product Name	4-Methyl-5-Thiophen-2-Yl-2H-Pyrazole-3-Carboxylic Acid
CAS No.	890621-27-9
Molecular Formula	C9H8N2O2S
Molecular Weight	208.24 g/mol
Synonyms	4-Methyl-5-(thiophen-2-yl)-1H-pyrazole-3-carboxylic acid; 5-(Thiophen-2-yl)-4-methyl-1H-pyrazole-3-carboxylic acid; 4-Methyl-5-(2-thienyl)-1H-pyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 4-methyl-5-(2-thienyl)-; 890621-27-9; 4-Methyl-5-thiophen-2-yl-2H-pyrazole-3-carboxylic acid; 4-Methyl-5-(2-thienyl)-1H-pyrazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Methyl-5-Thiophen-2-Yl-2H-Pyrazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.