Description

4,5,6,7-Tetrahydro-3-(Trifluoromethyl)-1H-Indazole is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core indazole scaffold, functionalized with a trifluoromethyl group, makes it a critical intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science: Investigated as a building block for advanced organic materials, such as liquid crystals or organic semiconductors.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies due to its distinct fluorine signature.
• Custom Synthesis: Provided to contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex fluorinated heterocycles.

Basic Information

Product Name	4,5,6,7-Tetrahydro-3-(Trifluoromethyl)-1H-Indazole
CAS No.	890005-22-8
Molecular Formula	C8H9F3N2
Molecular Weight	190.17 g/mol
Synonyms	3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole; 3-(Trifluoromethyl)-4,5,6,7-tetrahydroindazole; 1H-Indazole, 4,5,6,7-tetrahydro-3-(trifluoromethyl)-; 890005-22-8; 4,5,6,7-Tetrahydro-3-trifluoromethyl-1H-indazole; 3-Trifluoromethyl-4,5,6,7-tetrahydro-1H-indazole
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydro-3-(Trifluoromethyl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.